Dental product manufacturer Dentsply Sirona plans to end all production activities at its West College Avenue, York manufacturing facility following losses in the second quarter of 2020.

The Fortune 500 is out and a number of companies in Central Pennsylvania and the Greater Lehigh Valley have made the cut.

Dentsply Sirona is moving its executive offices to Charlotte, North Carolina, home of its new U.S. commercial hub. The headquarters relocation is not expected to impact its other offices and manufacturing operations in York.