Tait Towers Manufacturing laid off 257 employees from its corporate headquarters in Lititz at the end of March.

Five businesses in the midstate have filed WARN notices announcing layoffs or closures.

Pharmaceutical distribution company McKesson Corp. will permanently shut down its Middletown distribution center in April to move operations to a newly opened center in Bethlehem.

Veritiv Operating Company is closing its Lemoyne warehouse by the end of the year and plans to move a portion of the under 100 employees affected to its warehouse in Mechanicsburg.

Three Mile Island’s final power generator is closing next month, affecting 112 Exelon Generating Company employees.